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There will be no Shkodran Mustafi when Arsenal take on Southampton later today due to the groin problem he picked up against Manchester United last weekend.
With Mustafi’s absence in mind, Arsene Wenger rested Per Mertesacker in midweek to ensure his captain would be fit to fill in for his compatriot on Sunday.
In a 4-2-3-1 system Jack wilshere could start in the centre of the attacking trio behind Alexandre Lacazette, with Alexis Sanchez and Mesut Ozil on either side.
Aaron Ramsey and Granit Xhaka would then be the central midfield duo, behind a back four of Hector Bellerin, Laurent Koscielny, Nacho Monreal and Sead Kolasinac.
Arsenal: Cech, Bellerin, Koscielny, Monreal, Kolasinac, Xhaka, Ramsey, Wilshere, Ozil, Sanchez, Lacazette.