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The big decision facing Arsene Wenger ahead of Thursday night’s crucial game in Madrid revolves around Henrikh Mkhitaryan.
The Armenia international returned after six weeks out with a knee injury at Old Trafford on Sunday and marked the occasion with a goal.
He was replaced in the second half, however, after taking a knock to the same knee and Wenger said after the game that the playmaker would have to be assessed closely this week before a decision was taken on whether he could feature in Madrid.
Mkhitaryan came through training on Wednesday and has travelled with the squad, so Wenger now has to decide whether to start him as part of his three-man attack, or stick with Danny Welbeck, who has performed well in his absence.
Welbeck could be an appealing option as he would offer more in terms of a defensive viewpoint, but Mkhitaryan is more likely to create something than the England man.
With Arsenal needing to score in Madrid, a front three of Mesut Ozil, Alexandre Lacazette and Mkhitaryan is likely, providing the latter has proved his fitness.
The midfield three picks itself with Aaron Ramsey and Jack Wilshere coming back in having been given a rest at Old Trafford on Sunday to link up again with Granit Xhaka.
Konstantinos Mavropanos was magnificent against United on Sunday, as was Calum Chambers – with the young duo really impressing in the heart of defence.
But it’s unlikely Wenger will start with either in Spain, with skipper Laurent Koscielny and Shkodran Mustafi expected to return to the back four alongside Hector Bellerin and Nacho Monreal.
David Ospina played in goal against United, leading to suggestions Petr Cech may come in against Madrid – but it will be the Columbia international who starts on Thursday night.
Expected Arsenal XI: Ospina, Bellerin, Mustafi, Koscielny, Monreal, Xhaka, Ramsey, Wilshere, Mkhitaryan, Lacazette, Ozil.