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The Gunners travel to Germany to take on Eintracht Frankfurt hoping to start the journey which will see them go one better than last season.
Defeat against Chelsea in the final in Baku last season was a real blow for Unai Emery’s side, particularly after missing out on a top four finish in the Premier League.
Arsenal will be determined to get back to winning ways after a disappointing draw against Watford where a second half collapse cost them the points at Vicarage Road.
But to get the win Emery will be hoping his team can put in an improved display.
Here’s the latest Arsenal injury news and expected return dates.
Arsenal have been dealt a major injury blow, as the club have confirmed that the striker will be out of action until at least October with an ankle injury.
A statement via the club’s official website reads: “After assessments to an ongoing ankle issue, we have advised that Alex will need to rest and strengthen his ankle to regain full fitness.
“Alex has been playing through this injury for several weeks. He is likely to be back in action in October.”
On the announcement of the injury, the Frenchman has posted a message to fans on social media.
“Already started my rehab and looking to the future.. Thanks everyone for your messages!!” He wrote.
Lacazette is likely to miss at least five Arsenal games, including tonight’s Europa League opener vs Eintracht Frankfurt and the trip to Old Trafford to take on Manchester United in the Premier League.
Has struggled with injuries during his brief spell at Arsenal.
A groin strain kept the Greek defender out for much of the 2018/19 season and while he returned towards the end of the campaign, a further groin injury hampered his progress further during pre-season.
However, in an injury boost to Arsenal the 21-year-old played 67 minutes of the Premier League 2 match against Leicester City on Saturday, a game in which the Gunners won 2-1.
Rob Holding is another player who is close to returning to first team action, the defender played the full 90 minutes of the development squad’s win over Leicester City on Saturday, appearing to come through unscathed.
Giving an update on the player during his pre-Watford press conference, Arsenal manager Unai Emery hinted that the defender is close to a first team return.